Yeah, on the conlang mailing list it comes up along with a few other conlangs as potentially not-human usable systems. Maybe it would require a few generations of native speakers, since kids seem so much better at learning crazy difficult languages.
I tend to be kind of lazy when it comes to foreign languages. I won't look up every single word when I read, and I won't invest an hour doing the same writing a sentence. So I read Icelandic (can't/won't) write it and I write toki pona. The level of effort seems appropriate for hobbies. The level of effort for Ithkuil is beyond a hobby, except maybe a singular feat to translate a single sentence or paragraph. With that sort of personal economics reasoning going on, I can't imagine Ikthiul attracting a community that does more than talk about the language.
ike a! tenpo ale la mi sitelen kepeken toki Inli. (Oh, the irony that I write so much in English about toki pona on this forum)